Procedure Library
P17.4

Moisture Content Determination — Karl Fischer Titration and Oven Drying

Procedure 4 of 40 · Chapter 17 · §17.1.5

1 table 0 notes

Table 1

Sample TypeExpected MoistureRecommended MethodPrecision (% RSD)Analysis Time
Liquid surfactants (SLES, LABSA)0–70%Karl Fischer (volumetric)0.5–1.0%5–10 min
Oils, nonpolar solvents<0.5%Karl Fischer (coulometric)1–2%5–10 min
Powdered builders (STPP, zeolite)0.5–5%Oven drying at 105°C1.5–2.5%3–5 h
Solid polymers (CMC, PVP)3–10%Oven drying at 105°C1.5–2.5%3–5 h
Enzyme granules (coated)3–8%Karl Fischer (oven if KF unavailable)1.0–2.0%5–10 min / 3–5 h
Sodium percarbonate0.5–2%Karl Fischer (vacuum oven alternative)0.5–1.0%5–10 min