P21.2
High-Viscosity Product Manufacturing
Procedure 33 of 40 · Chapter 21 · §21.1.3
1 table 0 notes
Table 1
| Parameter | Standard Viscosity (200–2,000 mPa·s) | High Viscosity (>3,000 mPa·s) |
|---|---|---|
| Thickener type | None, or salt-thickened | HEC, CMC, HPMC, or associative polymer |
| Thickener level | 0–0.5% | 0.5–3.0% |
| Pre-dispersion method | Not required | Slurry in glycol, or powder induction |
| Primary mixer type | Paddle or anchor stirrer | Anchor with wall scrapers |
| High-shear homogenizer | Optional, 1,500 RPM | Required, 1,500–3,000 RPM |
| Mixing time (total) | 45–90 min | 90–180 min |
| Deaeration method | Static hold (optional) | Vacuum deaeration (required) |
| Deaeration time | 0–15 min | 15–45 min |
| Batch temperature (max) | 45 °C | 40 °C |
| Filtration | 10–25 μm bag filter | 25–50 μm (viscosity limits fine filtration) |