Hospital-Grade Disinfectant

Ingredients

Component	INCI / Chemical Name	Function	% w/w
BAC 80 % solution (or DDAC 80 %)	Benzalkonium chloride (or Didecyldimethylammonium chloride)	Active disinfectant	3.13
Alkyl polyglucoside (C8–C16)	Coco-glucoside	Wetting, detergent action	4.00
Tetrasodium EDTA	Tetrasodium EDTA	Chelating agent	0.50
Sodium citrate	Sodium Citrate	Buffer, auxiliary chelator	0.30
Propylene glycol	Propylene Glycol	Hydrotrope, freeze-thaw stabilizer	2.00
Fragrance	Parfum	Odor masking	0.10
Deionized water	Aqua	Solvent	89.97
Total			100.00

Addition Order & Process

Procedure: Dissolve tetrasodium EDTA and sodium citrate in deionized water at 30–35 °C. Add propylene glycol. Introduce the BAC 80 % (or DDAC 80 %) solution with continuous mixing for 15 minutes. Add APG gradually and mix for 10 minutes. Add fragrance last. The final active QAC concentration is 2.5 % w/w. pH should be verified at 6.0–7.5.

Formulation Notes

This formulation elevates the QAC concentration to 2.5 % active, broadening the spectrum to include enveloped viruses (e.g., influenza, SARS-CoV-2) under EN 14476, which requires a log reduction in viral titre . An enhanced non-ionic surfactant and chelating system ensures performance in the presence of blood and proteinaceous soil typical of clinical settings.

Formulation Card FC-11.1-P: Hospital-Grade Disinfectant

Hospital-grade disinfectants must comply with the European tiered efficacy framework (EN 14885): suspension testing (phase 2, step 1) precedes surface-simulation testing (phase 2, step 2) . BAC at concentrations 0.05 % demonstrates virucidal activity against enveloped viruses, including SARS-CoV-2, with exposure times of 1–5 minutes . QACs are generally ineffective against non-enveloped viruses (e.g., norovirus) and bacterial spores; facilities managing these pathogens should rotate to chlorine-releasing or peracetic acid formulations as discussed in Chapter 12.